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Metoclopramide is an anti-sickness medicine and is used to help stop you feeling or being sick (nausea or vomiting) including: After treatment for cancer, such as radiotherapy or chemotherapy Migraine-related sickness Nausea post-operation Palliative, end of life care It is only available with a prescription. For migraines, you can also get metoclopramide combined with a painkiller with a prescription. Key information: Metoclopramide is taken normally for up to 5 days. Drowsiness and diarrhoea are the most common side effects. Drinking alcohol with metoclopramide should be avoided, as it will make you feel drowsy.